李蓓

发布时间:2025-12-02浏览次数:45

导师简介

姓名

李蓓

出生年月

197611

单位

湖北医药学院生物医药研究院

所属学科

基础医学-病原生物学

职称、职务

教授,硕士/博士研究生导师

E-mail

libei2381@sina.com

研究方向

1.感染性疾病致病机制与调控

2.肠道-免疫-致病菌相互作用


个人简介

李蓓,博士,二级教授,硕士研究生导师,楚天学者“特聘”教授,湖北省医学青年拔尖人才,湖北省杰青获得者。发表SCI 收录30余篇,参与编写专著4本,获发明专利1项。主持国家自然科学基金3项、国家教育部重点项目与湖北省教育厅优秀中青年创新团队项目。作为第一完成人获得湖北省科技进步二等奖1项。


代表作

Hui Wang, Feiyu Li, Li XuHyuntae Byun , JinMing Fan, Meng WangMoran Li,JunZhuBei Li(通讯作者). Contributions of Escherichia coli and its motility to the formation of dual-species biofilms with Vibrio cholerae,Appl Environ Microbiol,2021.7.

Meng Wang,Yujiao Tian,Li Xu,Fusheng Zhang,Huigai Lu,Moran Li, Bei Li(通讯作者), High Osmotic Stress Increases OmpK36 Expression through the Regulation of KbvR to Decrease the Antimicrobial Resistance of Klebsiella  pneumoniae,Microbiology Spectrum, 2022.6. 

③ Fusheng Zhang, Li Xu, Yan Meng, Yujiao Tian, Huigai Lu, Jichen Xie, Renhui Ma, Moran Li and Bei Li(通讯作者),KbvR mutant of Klebsiella pneumoniae affects the synthesis of type 1 fimbriae and provides protection to mice as a live attenuated vaccine,Veterinary Research,2022.9.  

Li XuMeng WangJie YuanHui Wang, Moran LiFusheng Zhang,Yujiao Tian, Jing Yang, Jingjie wang, Bei Li(通讯作者)The KbvR regulator   contributes to capsule production, outer membrane protein biosynthesis, anti-phagocytosis and virulence in Klebsiella pneumoniaeInfection and immunity, 2021.2.

⑤ Long LiuFeiyu LiLi Xu, Jingjie Wang, Moran Li, Jie Yuan, Hui Wang, Ruiping YangBei Li(通讯作者),Cyclic AMP-CRP represses the transcription of tolB and rcsF to regulate the cell morphology of Klebsiella pneumoniae2020.1Frontiers in Microbiology.

Wei Peng, Yafei Xu,Yilin Yin, Jichen Xie, Renhui Ma, Guoyuan Song, Zhiqiang Zhang, Qiuhang Quan, Qinggen Jiang, Moran Li, Bei Li(通讯作者). Biological characteristics of manganese transporter MntP in Klebsiella pneumoniae,2024. 6, mSphere.

Jichen Xie , Hui Wang , Renhui Ma , Jinming Fan, Qiuhang QuanZhiqiang Zhang, Moran Li , and Bei Li(通讯作者);The molybdate transport protein ModA regulates nitrate reductase activity to increase the intestinal colonization and extraintestinal dissemination of Klebsiella pneumoniae in the inflamed gut2025,2,Virulence.